REF:

E2101 (Microwell Plate)

INTENDED USE:

This kit is an enzyme-linked immunosorbent assay for qualitative detection of IgG antibodies to Mycobacterium tuberculosis in human serum or plasma. It is intended for diagnosing and monitoring of patients related to infection by M. tuberculosis and other Mycobacteria.

SUMMARY:

It has been estimated that more than 1.7 million people were infected with Mycobacterium tuberculosis (MTb) in 1990 and this number increase every year due to new infections (HIV) and immigration. Now, with worldwide prevalence of 30 million cases and an incidence of 10 million new cases each year, tuberculosis (TB) is one of the most important health threatening problems worldwide.

IgG antibodies to MTb are routinely investigated in chronic infections and allow monitoring and management of the patients during treatment because inefficient therapy normally is characterized by increasing of the synthesis and excretion IgG. On the other hand, low levels of IgG in an inactive disease state indicates the non-evacuation of intra cellular infectious pockets with possible progression of the disease to active at later state.