REF:

C8407 (Strip)

C8408 (Cassette)

INTENDED USE：

Tricyclic Antidepressants Urine Test is a lateral flow chromatographic immunoassay for the detection of Nortriptyline (metabolites of Tricyclic Antidepressants) in human urine at a cut-off concentration of 1000ng/mL. This assay provides only a preliminary analytical test result. A more specific alternate chemical method must be used in order to obtain a confirmed analytical result. Gas chromatography/mass spectrometry (GC/MS) is the preferred confirmatory method. Clinical considerationand professional judgment should be applied to any drug of abuse test result, particularly when preliminary positive results are used.

SUMMARY：

TCA (Tricyclic Antidepressants) are commonly used for the treatment of depressive disorders. TCA overdoses can result in profound central nervous system depression, cardiotoxicity and anticholinergic effects. TCA overdose is the most common cause of death from prescription drugs. TCAs are taken or sometimes by injection. TCAs are metabolized in the liver, both TCAs and their metabolites are excreted in urine mostly in the form of metabolites for up to ten days. The TCA is a rapid urine-screening test that can be performed without the use of an instrument. The test utilizes a monoclonal antibody to selectively detect elevated levels of nortriptyline in urine. The TCA yields a positive result when the nortriptyline in urine exceeds 1000ng/mL.