REF:

C3104 (Cassette)

INTENDED PURPOSE:

NOVAtest® Dengue IgG/IgM Antibody Joint Test is an immunochromatographic assay that use immuno-capture method for qualitative detection of anti-dengue virus IgG/IgM antibodies from serum, plasma and whole blood specimens of human. It’s used as an aid in the diagnosis of the presumptive distinction between a primary and secondary dengue infection. This device is performed manually.

INTENDED USER:

Performance of the test is limited to laboratory professional use.

SUMMARY:

Dengue is a highly endemic infectious disease of the tropical countries. Dengue virus have 4 serotypes (DENV 1-4) in nature and is transmitted within humans through female aedes, 99% of which are caused by just two species, Aedes aegypti and Aedes albopictus. Classic dengue fever is primarily a disease of older children and adults. The incubation period varies from 3 to 14 days (average 4 to 7 days).

Primary dengue infection is associated with mild to high fever, headache, muscle pain and skin rash. Immune response includes IgM antibodies produced 5 days after symptoms onset and persist for 30-60 days. Secondary infections often result in high fever and in many cases with haemorrhagic events and circulatory failure. Immune response includes IgG antibodies rise in 1-2 days and IgM response after 20 days of infection.

Current dengue test methods include: MSE antigen test, RNA nucleic acid test and the RDTs. As a RDT product, NOVAtest® Dengue IgG/IgM Antibody Joint Test is intuitive, fast, easy to interpret results.