REF:

C2408 (Cassette)

INTENDED USE：

Group O1 Vibrio Cholera Antigen Test is a rapid and convenient immunochromatographic in vitro assay. It is used for detection of vibrio cholera O1 Inaba and vibrio cholera O1 ogawa in the specimens of feces or environment water. Vibrio cholera O1 is widely acknowledged as one of the most important pathogen causing gastrointestinal disorders. This assay provides a visual, qualitative result. Clinical expertise and professional judgment should be sought to further evaluate the results of the test. It is intended for professional use.

SUMMARY：

V. cholera O1 is a gram-negative pathogen to cause cholera epidemics, a devastating disease of immense global significance in many developing countries. It is generally transmitted to human via contaminated water and food. Vibrio Cholera O1 is divided into 2 biotypes, E1 Tor and classical. Each of the biotypes contains 3 serotypes named Ogawa, Inaba and Hikojima. The differentiation of the 3 forms of V. cholera O1 has only limited epidemiological value. Clinically, cholera may range from asymptomatic colonization to severe diarrhea with massive fluid loss, leading to dehydration, electrolyte disturbances, acidosis, circulation disorders and death. V. cholera O1 causes this secretory diarrhea by colonization of the small intestine and production of a potent cholera toxin. Because of the clinical and epidemiological severity, it is critical to determine as quickly as possible the presence of V. cholerae in clinical specimens, water and food so that appropriate monitoring and effective preventive measures can be undertaken by public health authorities. Nova One step V. cholera O1 Test is a chromatographic immunoassay for the qualitative detection of V. cholera O1 (vibrio cholera O1 Inaba and vibrio cholera O1 ogawa) in human feces, rectal swab specimens or water. The test is very sensitive to detect as little as 104 CFU/ml of V. cholera O1 in specimen solution.